Hepatic necrosis with doxapram hydrochloride.
نویسندگان
چکیده
منابع مشابه
Influence of Doxapram Hydrochloride on Recovery from Thiopental Anaesthesia.
MAN~ DaWS known as respiratory stimulants have been covely from pmsonmg by barbiturates and other sedat:ve have also been used to inmate and sustain breathing accelerate the rate of recovery from general anaesthes:a mon practice m years past has been to add carbon dmnl, of an anaesthetac to accomphsh this goal Even thoug prachces may be inherently dangerous, they are still used Recently, severa...
متن کاملThe Analeptic Effects of Doxapram Hydrochloride on Thiopentone Induced Depression.
A study of the analeptic properties of doxapram hydrochloride, as judged by its effects on the depression induced by moderate doses of thiopentone, was carried out in sixty patients. Three dose levels of the drug were employed, all of which produced marked increases in alveolar ventilation. These increases were due almost entirely to effects on tidal volume. Although the initial peak of stimula...
متن کاملDoxapram Hydrochloride Aggravates Adrenaline-Induced Arrhythmias Accompanied by Bidirectional Ventricular Tachycardia
Objectives. Doxapram hydrochloride is a respiratory stimulant that has an inhibitory effect on myocardial IK1 potassium channels and is thought to increase membrane instability and excitability in myocardial cells. We examined the arrhythmogenic effects of doxapram hydrochloride in a rat model of halothane adrenaline-induced arrhythmia. Methods. Thirteen female Wistar rats (12-14 weeks old) wer...
متن کاملMassive hepatic necrosis with large regenerative nodules
Massive hepatic necrosis (MHN) is characterized by extensive panlobular and multilobular hepatocyte necrosis, and is the morphological counterpart of acute fulminant liver failure. Histopathologic examination of explanted liver specimens reveals a wide spectrum of morphological changes in the parenchyma, from areas of extensive hepatocyte loss and parenchymal collapse to areas of hepatocytic re...
متن کاملAcute hepatic necrosis and fulminant hepatic failure.
Fulminant hepatic failure' is defined as severe, acute impairment of hepatic function culminating in hepatic encephalopathy, the encephalopathy being the result of hepatocellular failure and supervening within three weeks of the onset of symptoms*. This definition excludes the hepatic encephalopathy of hepatic cirrhosis and of chronic hepatitis, which produces a slightly different clinical pict...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1985
ISSN: 0032-5473
DOI: 10.1136/pgmj.61.719.833